Zinc finger peptide cleavage by a dinuclear platinum compound.
نویسندگان
چکیده
Electrospray ionisation mass spectrometry (ESI-MS) and {(1)H, (15)N HSQC} NMR spectroscopy has elucidated the binding of a dinuclear platinum compound to a zinc finger peptide with induced backbone cleavage. Cleavage is selective on the N-terminal side of the cysteine residue following incubation at neutral pH, and is further dependent on structure of dinuclear compound.
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عنوان ژورنال:
- Chemical communications
دوره 49 62 شماره
صفحات -
تاریخ انتشار 2013